Best Berberine Supplements 2020 (Top 7 Buying Guide)

7 Best Berberine Supplements 2020

In a rush? Here are our Top 3 Overall…

These days, we are quick to buy dietary supplements that solve our health problems. These target different issues, from weight loss to bone strength. We get enticed, not considering that they are full of chemicals or caffeine. But if you want a supplement with nothing but the goodness of nature to solve multiple problems, it’s time to explore the best berberine supplements.

If you are into health and fitness, you have probably heard of berberine, a chemical that comes from different plants. It is a multi-functional gift of nature, offering a number of benefits to improve your heart and brain health. It even allows you to stay in shape and keep obesity at bay. But what exactly is the plant compound used for, and which is the best berberine supplement?

Top 7 Best Berberine Supplements 2020 Reviews

So you now know about the benefits of berberine supplements. But who makes the best berberine supplement? It’s time to find out about the best brands of berberine supplements that can help you stay healthy in many ways. Let’s take a look!

1. Nuzena Berberine Pure +

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Best Features:

  • Suitable for both men and women
  • Affects body at a molecular level
  • Boosts weight loss and and activates AMPK (Metabolic Master Switch)
  • Improves heart health and healthy cholesterol management
  • Increases glycolysis to help body break down sugars
  • Gives energy and alleviates brain fog
  • Made from extracts of sustainably sourced ingredients
  • Made in safe facilities and clinically proven to be healthy
  • Comes with your very own health specialist (Free Consultation!)

Nuzena Berberine Pure+ Review:

If you are looking for a berberine supplement that can handle multiple health problems and leave long-term results, Nuzena Berberine Pure + is an excellent option for you. People who take this supplement swear by its effectiveness on their metabolism, diabetes, and other conditions.

The supplement uses pure extracts of ingredients that are clinically proven to be safe. The supplement is developed in facilities registered with the FDA. You have to take two capsules a day (and no more than that). It’s recommended that you consume them about half an hour before your two daily meals. Nuzena is such as amazing company in which you can talk to a specialist to receive a totally free consultation!

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2. BulkSupplements Berberine HCL

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Best Features:

  • Reverses aging process and maintains cellular health and longevity
  • Less costly than most other supplements and antibiotic options
  • Boosts energy, controls sugar, supports healthy digestion and weight management
  • High strength of berberine in each capsule for an aggressive approach
  • Free from allergy

BulkSupplements Berberin HCL Review:

The second rated product on our list of the best berberine supplements is the Berberine HCL. At 500 mg powder per serving equaling 1/4 tsp, this berberine supplement offers a higher berberine concentration in each serving than most of the other berberine supplements.

This supplement is designed to give you a purely natural way of staying young and fit for a long time. Its level of purity has been tested and proven in third-party labs. It works better than costly antibiotics and helps with weight management, sugar levels, digestion, and more.

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3. Thorne Research Berberine-500

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Best Features:

  • Provides gastrointestinal microbial balance and maintains weight
  • Boosts immune system, maintains blood sugar levels, and limits cholesterol
  • Highly effective in different conditions that berberine targets
  • Pure, safe, and natural ingredients with no harmful additives
  • Formulated on the basis of scientific research to bring you the miracle of the herb

Thorne Research Berberine-500 Review:

The next product on our list of Berberine supplements is the Thorne Research Berberine-500. If you’re just starting out and want to see how your body reacts to berberine, this supplement may be ideal for your new journey. It brings together the magic of ancient herbal practices and modern studies.

This high-quality berberine supplement, with calcium laurate and hypromellose content, comes with multiple health benefits. It is one of the best berberine supplements for PCOS and maintains healthy bacteria in the gut. It is also free from gluten, dairy, and soy and only has natural ingredients.

4. Sunergetic Premium Berberine

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Best Features:

  • Natural treatment to enhance immunity
  • Supports gastrointestinal health for weight management
  • Advanced formulation for easy consumption and absorption
  • Developed in a safe environment and ideal for people with sensitive systems
  • Designed with pure berberine, with no fillers or additives

Sunergetic Premium Berberine Review:

An advanced berberine supplement designed to offer 1200 mg of berberine in a single day – Sunergetic Premium Berberine capsules make it easy to track your consumption. Even people who have difficulties swallowing pills find it easy to consume these capsules. The supplement brings you good health.

It is developed in facilities registered with the FDA and is considered as one of the safest berberine supplements to address your health conditions in a steady, natural way. It is free from fillers, thus giving you pure berberine in every capsule. It is perfect for people who have a highly sensitive system.

5. Dr. Whitaker’s Berberine

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Best Features:

  • Maintains glucose and insulin levels within a healthy range
  • Controls cholesterol levels to maintain heart health
  • Scientifically backed natural supplement to address multiple health problems
  • Designed to give you 1500 mg of berberine in a single serving
  • Trusted and recommended by physicians

Dr. Whitaker’s Berberine Review:

Dr. Whitaker’s Berberine is one of the few dietary supplements that has succeeded in earning the faith of practicing doctors. It is formulated on the basis of research that suggests a dosage of 1500 mg of berberine a day. So, if you want to have a large concentration of berberine, this capsule is ideal for you.

Every bottle of this supplement comes with 90 capsules, each with 500 mg of berberine. So, for the takers of 1500 mg of berberine daily, this supplement makes it convenient to track the consumption. It is a natural medicine to provide the goodness of traditional practices – but in a controlled, scientific way.

6. NOW Supplements Berberine Glucose Support

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Best Features:

  • Maintains levels of lipid and glucose within a healthy level
  • Formulated to maintain gastrointestinal comfort
  • Combined with superfood MCT oil for increased absorption
  • High-grade supplement that’s tested and certified as safe
  • Designed by a trusted brand in the dietary supplement scene
  • ns, GMOs, sugar, etc., and is absolutely safe

NOW Supplements Berberine Review:

The berberine supplement from the house of NOW Supplements is one of the most trusted. It is formulated to be absorbed easily by your body, thanks to the presence of a triglyceride called C10. It comes from MCT oil, a product that has fast become popular among dieters due to its health benefits.

Together with MCT oil, this berberine supplement contributes to gastrointestinal protection and comfort for a healthy body. It is tested and certified as a safe supplement. The supplement is manufactured by NOW, a brand operating since 1968 and considered one of the stalwarts of the supplement industry.

7. WellBetX Berberine

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Best Features:

  • Maintains cardiovascular health by controlling cholesterol levels
  • Boosts glucose metabolism to help digest carbs and control blood sugar
  • Ideal for new users with 1000 mg of berberine in one serving
  • Certified by a third-party lab as a safe and pure product
  • Tested with advanced technology to prove that it is free from 700 contaminants

WellBetX Berberine Review:

The final product on our list of the best berberine supplements is WellBetX Berberine from Natural Factors. This supplement is made from berberine that has been naturally derived from a sustainable source, i.e., the roots of barberry. It is clinically tested as a potent medicine for several health conditions.

Each capsule contains 500 mg of berberine and is perfect for those who are just beginning their berberine supplement journey. It has been tested using advanced technology in a third-party lab that certifies it free from contaminants and GMOs and proves its purity. It is also free from allergens.

Our Choice of Berberine Supplement:

We have tried and tested the highest-rated supplies to filter out the top seven berberine supplements. Of all these supplements, our top pick is the Nuzena Berberine Pure +. It is a complete package of the best features without burning a hole in your pocket!

  1. Cost: Every bottle of 60 capsules is available at $40. But if you purchase in bulk, you can get several months of supply, available at an unbelievable price. The bulk prices are as follows:
  • 2 bottles at $75 (Savings – $5)
  • 4 bottles (Buy 3 + 1 Free) at $120 (Savings – $40)
  • 6 bottles (Buy 4 + 2 Free) at $160 (Savings – $80)
  1. Strength: Each capsule has 600 mg of berberine, which is a higher concentration than most other supplements. You have to take two capsules.
  2. Purity: This supplement is lab-tested to prove its purity, made in FDA-compliant facilities, and made of natural ingredients according to GMP guidelines.

You will not just get excellent effects by using this supplement. You’ll also find that it is much more cost-effective in the long run. That’s because it is stronger than many of its higher-priced competitors and definitely safer and cheaper than conventional medicines.

FAQ About Berberine Supplements

What is Berberine?

So now that you see the top berberine brands let’s talk further about what berberine actually is, and what it can do for your health. Berberine is a compound that can be extracted from a number of natural resources. One of the most well-known sources of berberine is the root of the barberry shrub. Another source is tree turmeric – but don’t confuse it with regular turmeric.

Berberine has been used in natural treatments like Ayurveda for thousands of years. It’s only recently that scientists started studying it to find out more about its qualities. Their findings have made berberine a noteworthy ingredient in health supplements.

In powdered form, berberine has a rich yellow color. Today, berberine supplements are available in the form of capsules or tablets, as well as extracts. The main advantage is that it targets not one or two issues but many health conditions – in a natural way.

What Are the Uses and Benefits of Berberine?

Berberine supplements have become popular because they are a natural way to help with inflammation, diabetes, cholesterol, heart health, weight issues, and much more. One of the most significant effects of berberine is on inflammation.

In addition to its anti-inflammatory properties, berberine is responsible for activating AMPK, which is an enzyme in the cell. This helps to boost the metabolic function in your body so that you can stay in shape and still enjoy a healthy appetite.

Because of its ability to regulate the composition of fat and also its positive effects on your lifespan, it is also referred to as a “master switch”. Found in a large number of herbs, it has several applications in pharmacology. Let’s take a look at how it helps your body:

a) Berberine for Type II Diabetes:

Several studies have been conducted to prove that berberine is effective in causing a decline in the sugar levels in the blood. It is, therefore, considered a promising remedy for diabetes. Taking sufficient amounts of it may be as effective as diabetes medicines.

Scientists believe that berberine can have a positive effect on the health of people with Type II diabetes by lowering glucose levels. It has also been found that berberine can improve your body’s sensitivity to insulin. As a result, the risks of kidney damage, besides controlling diabetes.

Further studies are indeed required to find out the extent of berberine’s effects on diabetes and determine the exact dosage of berberine to manage the condition. However, research so far has shown promise, and berberine supplements are already in use to help diabetic patients.

b) Berberine for Cholesterol:

Another medicinal property that berberine is known for is its effect on cholesterol. Studies show that berberine might be useful in lessening bad cholesterol. This is particularly true in the case of diabetic patients. You have to remember that diabetes rarely exists without other conditions.

Berberine’s effects can be boosted when it is combined with red yeast rice, and together, it protects you from cholesterol and prevents the side effects of other forms of treatments. Preliminary studies show that it boosts the liver’s ability to remove cholesterol and thus reduces lipids and fat levels in the blood.

c) Berberine for Weight Loss:

One of the reasons berberine supplements have become extremely popular is its effects on obesity. Many studies have been focusing on berberine’s ability to boost weight loss. While the evidence is still limited, the small number of research works has been conducted shows its possibility of fighting off obesity.

Berberine has been found to have moderate effects on weight loss, and it also lowers lipid levels. It also boosts metabolism, so the food you eat gets converted into energy efficiently. We know how obesity harms our quality of life. Many overweight people have found steady results by using berberine supplements.

d) Berberine for PCOS:

PCOS, or polycystic ovary syndrome, is a condition with which women get frequently diagnosed these days. Many women with PCOS have started taking berberine in the form of supplements and found some relief from it. Experts also believe that berberine can help women with PCOS.

It has recently been found that the effects of berberine on a female body are similar to those of the common medicines prescribed by gynecologists to control PCOS. It is also known to have moderate effects on insulin levels, ovulation rate, and fertility.

e) Berberine for Alzheimer’s and Parkinson’s:

Among the many positive effects of berberine is its capability to fight off Alzheimer’s Disease and Parkinson’s Disease. Scientists are studying the effects of berberine on neurodegenerative conditions and their ability to boost the pathways of neuroprotection.

More research is required to prove its exact abilities in this, but the initial studies have shown great promise for berberine to become a natural treatment for such conditions. It is also known to alleviate a decline in cognitive function or dementia.

f) Berberine for Heart Diseases

Berberine is effective in controlling several conditions that otherwise lead to heart diseases. From obesity to cholesterol, many diseases can be fought off by consuming berberine, and scientists are busy studying these effects of the compound.

It can be said that berberine also has the potential to protect your heart. It is also believed to be helpful in arrhythmias and failure. Experts believe it can boost nitric oxide release in your body. This leads to relaxed arteries. It also improves the flow of blood and can also lower your blood pressure.

The effects of berberine as a natural medicine are many. While it has been in use in different alternative treatments for about 2500 years, it is only that scientists and medical experts have started taking an interest in it. The number of studies is, therefore, limited. But even with few studies, it’s understood that berberine has many benefits. People using berberine supplements can vouch for its positive effects.

Who Should Buy Berberine Supplements?

So, you know what health benefits berberine has shown. While scientists are continuing their work focused on the benefits of berberine, it has become a popular ingredient in many high-quality health supplements. People with different health conditions have started using these.

If you want to improve your glucose regulation and insulin sensitivity, berberine supplements may help you. People with Type II diabetes have found massive help by using this supplement, and if you are suffering from the condition, you can try it, too.

Are you suffering from metabolic syndrome? Berberine supplements can be helpful. This condition, coupled with a bad diet plan, can lead to a number of problems, the most common among them being high levels of lipids and cholesterol. Berberine supplements can alleviate these.

In the form of a supplement, berberine has been proven beneficial for people who have metabolism concerns. As we just learned, berberine can reverse the causes and effects of obesity and help you stay fit and slim. It has gained huge popularity among people who want to lose weight and boost metabolism.

While berberine alone may not have magical effects on weight loss, it can help reduce body fat and the impact of obesity on the body in the form of a supplement, especially when combined with other ingredients that can help you stay fit. Its effects are mainly on your overall health.

Researchers who believe in the effects of berberine on weight loss are still studying to compare its results with other natural products that aid weight loss, such as green tea. The primary impact is on your metabolic health, which eventually leads to a loss of weight, and you can stay healthy.

A large number of people with Irritable Bowel Syndrome also swear by berberine supplements. Studies have shown that it can affect the symptoms of IBS, even though the exact reason behind this is not yet known to researchers. It can also help patients with gastrointestinal conditions.

Are There Any Beneficial Berberine Stacks?

While berberine, on its own, can affect different health conditions moderately, its effects multiply when paired with other ingredients in the form of powerful supplements. These are commonly referred to as berberine stacks. These offer a synergy of the strengths of complementary components.

Take a look at the top three berberine stacks:

a) Berberine with Quercetin

Berberine, when teamed with quercetin, forms a stack that is helpful in reducing inflammation. This stack is also useful in boosting the immune system of the body. Quercetin itself is known for its antioxidant properties that help to keep diseases away, alongside the antihistamine effects. It also protects the heat, thus complementing the effects of berberine.

b) Berberine with Milk Thistle

Berberine’s ability to prevent liver inflammation combines well with the natural power of milk thistle to protect the liver from toxins and swelling. In fact, milk thistle’s properties have maintained its status as a popular herbal medicine for over two millennia. Together, berberine and milk thistle form a stack that strengthens your digestive and immune systems. It also flushes out toxins and alkalizes your body.

c) Berberine with Goldenseal and Oregon Grapes

Both Oregon grapes and Goldenseal are rich in berberine. When these natural sources are combined with additional berberine, the final result is full of antioxidants of various varieties. Antioxidants help to keep diseases away, prevent oxidative stress, and slow down the aging process. They also strengthen your cardiovascular and digestive systems. Thus, you get a long, healthy, youthful life.

The effects of berberine are being studied by scientists, and they have so far found a moderate impact of the compound alone. But in the form of health supplements, berberine combines with other ingredients and proves to be incredibly helpful in different health conditions.

What are the Side Effects of Berberine?

Berberine is considered safe in general, with no severe health problems or side effects caused by its consumption. However, there are some random issues noticed during research. For instance, during one particular study to understand the effects of berberine on Type II diabetes, a few subjects were found to experience constipation after they went on berberine.

Some of the other research works have also led to the idea that it may affect the gastrointestinal tract and its behaviors. An overdose of berberine can make you experience cramps, flatulence, diarrhea, or other such temporary digestive problems. Usually, many people face such issues when they first start on any new dietary supplement.

Berberine is, after all, a natural ingredient. Do you think that you might be sensitive or allergic to any natural ingredient? Then it is a good idea to discuss the consumption of berberine supplements with your physician. This will help determine if the supplement you want to take is free from anything that might set off allergic reactions in your body, causing more harm than benefits.

Best Dosage of Berberine

Experts suggest that if you want berberine supplements to show the best results, it is a good idea to spread your consumption throughout the day. In clinical studies, the amount used ranged between 900 mg and 1500 mg every day. This is the total amount, divided into small doses and taken half an hour before each meal.

The best thing about berberine supplements is that they are usually in the form of capsules or tablets. Each of these is a serving, and you will be able to easily determine how many servings you should take from the recommendations by the brand. If you choose a supplement in the form of 450-mg capsules, you can take 2-3 of them in a day.

How Do I Pick a Good Berberine Product?

There are different types of berberine supplements available on the market. Supplements that use berberine HCL have been studied the most. These supplements are believed to be easily absorbed by your body, and hence, they are the most popular.

Another thing to note, at the time of buying berberine supplements, is the color of the supplement. As mentioned earlier, the color of berberine in powdered form is a rich yellow. So, a high-quality supplement will also be yellow. But make sure to check the label to see if it has artificial colors.


So, we can conclude from the above that berberine is known for its positive effects on your health – and the outcomes are many. Scientists have only just started studying the natural compound. As researchers continue to study this miraculous gift of nature, it’s positive effects on our body are getting revealed in front of us.

Berberine’s moderate effects on health are often increased when it is paired with other ingredients. The best thing is that as a natural product, the side effects of using berberine are temporary – and few. You can consult a physician and pick a wholesome berberine-rich dietary supplement that will give you all-around protection and health benefits.

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